Lee Hae-jo (Han Hye-jin) is a first year resident specializing in neurosurgery. She didn't graduate from a premier medical school, but she is determined to become the best neurosurgeon. Cha Yeo-wook (Song Chang-eui) is also a first year neurosurgery resident. Unlike Hae-jo, Cha Yeo-wook graduated from the best medical school and is the grandson of the chairman of the board at the Korea University Hospital. His background to become a doctor is impeccable. Kang Eun-hyun (Park Gun-hyung) is the chief resident of neurosurgery. A love triangle begins between these three people.